Background The clinical significance of submicroscopic levels of leukaemic cells in bone-marrow
aspirates from children with acute lymphoblastic leukaemia (ALL) remains controversial…

Aberrant genome-wide hypomethylation is thought to be related to tumorigenesis by promoting
genomic instability. Since DNA methylation is considered an important mechanism for …

Mucosal immunisation may be used both to protect the mucosal surfaces against infections
and as a means for immunological treatment of peripheral immunopathological disorders …

The purpose of this paper is to propose a theoretical model that integrates the different
groups of factors which influence the decision‐making process of international students, …

After De’s pivotal demonstration in 1959 of a diarrhoeogenic exo-enterotoxin in cell-free
culture filtrates from Vibrio cholerae (of classical biotype), much insight has been gained about …

A genetically engineered Vibrio cholerae strain from which the cholera toxin genes had
previously been deleted was used as a host in which to study the expression and secretion of …

Transfusion dependency seems to have a major prognostic impact in patients with
myelodysplastic syndrome (MDS) (Malcovati L et al. J Clin Oncol 2007; 25:3503). Preliminary data …

In this paper we study the assembly, in vivo and in vitro, of a family of hexameric, heat-labile
enterotoxins produced by diarrheagenic bacteria. The toxins, which consist of an A subunit …

Recent work has provided new insights into the pathogenesis of the potentially life-threatening
diarrheas caused by Vibrio cholerae and enterotoxigenic Escherichia coli (ETEC): a new …

In this study, we used multiparameter flow cytometry to quantify minimal residual disease (MRD)
in 165 serial bone marrow samples from 40 patients diagnosed with acute …